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Enfamil Reguline Baby Formula, Milk-Based Infant Nutrition, Dual Prebiotics for Soft, Comfortable Stools within 1 Week of Use, Omega-3 DHA for Immune Support, Reusable Powder Tub, 19.5 Oz​

4.7 4.7 out of 5 stars 1,974 ratings

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Purchase options and add-ons

Brand Enfamil
Size 1.22 Pound (Pack of 1)
Item Weight 20.4 Ounces
Allergen Information Tree Nuts, Lactose, Milk, Soy
Item Form Powder

About this item

  • 💩 COMFORT IN 1 WEEK: Dual-prebiotics, proven to help promote softer stools and ease occasional constipation within the first week of use.​
  • 🧠 NURTURING BRAIN DEVELOPMENT: Our formula has expert-recommended DHA, known to support your baby's growing brain, supporting their milestones with confidence.
  • 💧 IMMUNE-SUPPORTING NUTRIENTS: Enfamil Reguline has a blend of vitamins and that help support your little one’s immune system, easy-to-digest proteins, and 30 total nutrients for their development.
  • 🍼 PEACE OF MIND NUTRITION: Designed with care for babies up to 12 months, so you can feel confident in providing your baby with a formula that supports their digestive comfort and overall well-being.
  • 👨🏽‍⚕️ TRUSTED BY PARENTS & PEDIATRICIANS*: Enfamil is the #1 Trusted Infant Formula Brand By Pediatricians* & Parents and the #1 Pediatrician Recommended Brand for Brain-Building & Immune Support.​
  • SNAP ELIGIBLE: Eligible to be purchased with Supplemental Nutrition Assistance Program (SNAP) benefits

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From the brand


From the manufacturer

Reg RTB
Reguline supp facts 1
Reguline supp facts 2

Frequently Asked Questions

What is this formula for? Enfamil Reguline is designed to help ease your little one’s occasional constipation, promoting softer stools within the first week of use.
Why is DHA so important? Enfamil Reguline has expert-recommended omega 3 DHA, known to support your baby's growing brain and eyes.
What are the dual-prebiotics? Our dual prebiotic blend consists of galacto-oligosaccharides (GOS) and polydextrose. This blend of prebiotics is designed to help support your baby’s digestive health and help promote softer, more comfortable stools.
Does this help with gassiness? While Enfamil reguline is not specifically for tummy discomfort, it’s specially designed to help soften stools for babies with occasional constipation in as little as one week. We offer an assortment of solutions formulas for all of your little one's needs. To learn more, see the comparison chart below.
Reguline Infant baby formula milk gentle formula AR Sens infant formula baby milk DHA brain building
Enfamil Reguline Enfamil NeuroPro Gentlease Enfamil A.R. Enfamil Sensitive Enfamil NeuroPro Infant
Customer Reviews
4.7 out of 5 stars
1,974
4.8 out of 5 stars
5,342
4.7 out of 5 stars
2,731
4.8 out of 5 stars
2,173
4.8 out of 5 stars
6,771
Price $37.55 $38.88 $38.88 $34.68
Key Benefit Dual Prebiotic Blend for Softer Stools in 1 Week* and Vitamins and Minerals for Immune Support, has Brain Building DHA Relief from Fussiness, Crying, Gas & Spit-Up and has Brain Building DHA & MFGM Components, HuMO6* Gentle Immune Blend Added Rice Starch to Reduce Frequent Spit-Up in 1 Week* and has Brain Building DHA For Tummies Sensitive to Lactose and has Brain Building DHA, 2'-FL HMO for Immune Support Brain Building DHA & MFGM Components, HuMO6* Immune Blend
Brain Building DHA
For Fussiness, Crying, Gas & Spit-Up
For Frequent Spit-Up
For Lactose Sensitivity
Easy-to-Digest Proteins
Immune Support Dual prebiotics PDX and GOS *2'-FL-HMO¶, PDX, GOS, vit C & E, selenium, partially hydrolyzed protein, reduced lactose Dual prebiotics PDX and GOS 2'-FL HMO *2'-FL-HMO¶, PDX, GOS, vit C & E, and selenium
MFGM Components‡

Product Description

Enfamil Reguline Constipation baby formula with iron features a blend of probiotics and easy to digest proteins to promote soft, comfortable stools. For those times when your baby is struggling to poop, because no one is happy then. It is gentle so it can be used everyday to provide complete nutrition for your little one through 12 months of age. Help ease those hard to go scenarios and make her more comfortable with Enfamil Reguline. *Proven in Enfamil Infant Formula **QuintilesIMS, using the ProVoice Survey fielded from Janurary 2017 to December 31, 2017.

Product details

  • Is Discontinued By Manufacturer ‏ : ‎ No
  • Product Dimensions ‏ : ‎ 4.4 x 6.3 x 5.5 inches; 1.28 Pounds
  • Manufacturer recommended age ‏ : ‎ 0 - 1 years
  • Item model number ‏ : ‎ 167004
  • Date First Available ‏ : ‎ April 7, 2014
  • Manufacturer ‏ : ‎ Mead Johnson Nutrition
  • ASIN ‏ : ‎ B00JGPG60I
  • Country of Origin ‏ : ‎ USA
  • Customer Reviews:
    4.7 4.7 out of 5 stars 1,974 ratings

Important information

Safety Information

Do not use a microwave oven to warm formula. Serious burns may result. Refer to the product label for the most accurate information. Failure to follow these instructions could result in severe harm. Once prepared, infant formula can spoil quickly. Either feed immediately or cover and store in refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Do not use prepared formula if it is unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use formula within 1 hour or discard.

Ingredients

INGREDIENTS: WATER, PARTIALLY HYDROLYZED NONFAT MILK AND WHEY PROTEIN CONCENTRATE SOLIDS (SOY), VEGETABLE OIL (PALM OLEIN, SOY, COCONUT, AND HIGH OLEIC SUNFLOWER OILS), LACTOSE, CORN SYRUP SOLIDS, AND LESS THAN 2%: POLYDEXTROSE*, GALACTOOLIGOSACCHARIDES*, MORTIERELLA ALPINA OIL**, CRYPTHECODINIUM COHNII OIL†, RICE STARCH, DIACETYL TARTARIC ESTERS OF MONO- AND DIGLYCERIDES (DATEM), CALCIUM CARBONATE, CALCIUM PHOSPHATE, MAGNESIUM CHLORIDE, FERROUS SULFATE, ZINC SULFATE, CUPRIC SULFATE, SODIUM CITRATE, MANGANESE SULFATE, POTASSIUM IODIDE, SODIUM SELENITE, ASCORBIC ACID, VITAMIN E ACETATE, NIACINAMIDE, CALCIUM PANTOTHENATE, VITAMIN A PALMITATE, RIBOFLAVIN, THIAMIN HYDROCHLORIDE, VITAMIN B6 HYDROCHLORIDE, FOLIC ACID, VITAMIN K1, BIOTIN, VITAMIN B12, CHOLINE CHLORIDE, INOSITOL, VITAMIN D3, TAURINE, AND L-CARNITINE. *A TYPE OF PREBIOTIC **A SOURCE OF ARACHIDONIC ACID (ARA)†A SOURCE OF DOCOSAHEXAENOIC ACID (DHA) Please refer to your product packaging for the most accurate information.

Directions

baby formula

Legal Disclaimer

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

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Customer reviews

4.7 out of 5 stars
4.7 out of 5
1,974 global ratings
Enfamil Reguline is my go to formula.
4 Stars
Enfamil Reguline is my go to formula.
Enfamil Reguline has always helped my baby poop very regularly. This is the second time purchasing through Amazon and the first time receiving one with a broken seal. I’m not very impressed, especially since it was packed and shipped to me in that condition. That’s money gone down the drain since I had to throw it away.
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Top reviews from the United States

Reviewed in the United States on January 18, 2016
Our little girl was strictly formula fed from day one, and left the hospital using Enfamil Newborn, which worked great...for a while. She never spit up the whole four weeks she was on it, which was great, but we also found that she also didn't have a bowel movement every day or every other day like most newborns, and she also had tons of gas! Talk about a little tooter! She was going every three to four days with normal looking stool, and on her fourth week I started noticing her little tummy slightly distended, and then all chaos broke out with fussiness, extreme gas, and little sleep for both of us. Our pediatrician recommended Enfamil Gentlease, so we went out and started implementing the new formula into her diet. Everything went well for about a week and a half, and I was so happy as she started going a little more regular for the first two days. Apparently that was only her body getting used to the new formula, because after that we noticed her straining with no bowel movement. I, being a new mom, freaked out, and from the doctor's directions gave her dark Karo syrup, but this didn't work either, and we ended up with having to use a suppository. And poor baby was so constipated from the Gentlease that it was a virtual nightmare that I would love to forget, but after struggling to go for an hour and a half with the suppository we finally had success, and a new formula to try from the doctor's orders. This time around we were told to use Enfamil Reguline, and I was very skeptical especially since I kept reading reviews of babies with diarrhea from this formula. But after seeing my little baby struggle like that I was desperate to try anything. Luckily she took this formula with ease, and we happily said bye bye to constipation! We started this formula at night, and the next day gave her Karo syrup, and right after that she had a bowel movement that got the rest of the hard stool out. She did have one explosive diaper later in the day, but I do believe that was a mixture of the Karo syrup and the Reguline working. From then on out she has been going wonderfully every other day with normal stool, no straining whatsoever any more, and I have a much happier baby! She does toot quite a bit on this new formula, but she's otherwise had no issue of gas staying inside of her. Reguline also does seem to be a little thicker than the other two formula's we've tried, and I have noticed it does stain a bit more. Our daughter also spits up, but not horrible amounts either on this one. She was spitting up a lot more on the Gentlease. Otherwise this formula has been great for us, and we will continue to use it! On the downside there are no refill packs (seriously Enfamil? What's up with that?), and I live in a small community and only Wal-Mart carries this formula, and even then they have a tiny supply so when I do buy formula I make sure to buy enough for a few weeks...which equals a lot of $$ being spent. I've also heard people who have WIC cannot use it for this formula, but since I don't have WIC I'm not sure if it still stands.

Again, great formula, works like a charm for my daughter, no more constipation with normal baby stools, minimal spit up, and smelly toots, but the cons are no refill packs available or bulk orders available, and Reguline is not readily available in stores. Since this works for my daughter I'm staying on it, but Enfamil needs to see how many people are using this and come out with refill packs.

**Update as of 6/15/16**

Our daughter is almost seven months now, and still uses this formula. We've introduced food for a few months now, and even with the food she still manages to go almost every day, some days twice! If, and it's a big if, she doesn't go we give her half/half juice mixture with baby water, and that does the trick! We started her on the Parent Choice stage 2 juice of prune/apple, and that works perfectly!! She more than likely will go twice the next day, but we still haven't had any issues at all like we did! She might have a hard stool one day, but the next day it will be soft either by the formula she drinks, or by the juice we give her. Reguline is still the best formula out there for our little one!
60 people found this helpful
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Reviewed in the United States on September 22, 2020
I read all reviews prior to purchasing & I was on the fence, yet hopeful. And thank goodness I made the purchase.

My LO is 5 weeks old, and was exclusively BF for the first couple of weeks then long story short my supply was not keeping up with the demand. So I began to supplement and was suggested Similac Advanced-Blue Can. (It was ok for a week and then it went down hill. Extreme fussiness, tight tummy, trouble burping and worst of all constipation.)

Next, we tried Similac Pro Sensitive (Orange Can) it was an obvious difference immediately after feeding, burping was easier, baby appeared to be happier at first but constipation worsen.

She went from 1-2 days of no BM to 2-3 and was sooo uncomfortable. So I did some research and found this Enfamil.

I begin giving baby Enfamil at 4 pm on 9/20. She had a little quarter sized poop 24 hours later but was still backed up obviously. But calm and not quite as tense or fussy like with Similac. By 9:30 tonight (roughly 29 hours later she had a large BM. Loose consistency, not quite diarrhea & dark green.)

I am grateful this formula worked for our LO. She has had consistent Enfamil every feeding since yesterday. I will update on whether it will become her full time formula or alternative on certain feeds.

Update: 7 months later. Still using this formula and will continue to use until she is no longer on formula. I swear by it. Hands down.
43 people found this helpful
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Reviewed in the United States on March 27, 2022
Our baby girl started having issues with hard stools when she was about three weeks old. We started her on Similac pro advance then tried Similac total comfort, enfamil neuro pro, enfamil gentlease, enfamil enspire and Gerber Soothepro. None of them helped. She wouldnt go for 2-3 days, would grunt and push nonstop and cry. When she finally did go it was hard. not soft like it should be. She was miserable. Her pediatrician sent her to a GI specialist and they couldn't find anything wrong. We felt so bad for her. Then we finally found enfamil reguline! It's a little bit more expensive than other formulas but totally worth it because it works!! She now goes daily, it's soft, she doesn't grunt and push all the time or cry when she goes. We have a happy healthy baby girl. I recommend this formula to anyone who's baby is having constipation issues. We buy it on Amazon when it's in stock for convenience and never have any issues with packaging, it's never outdated and it's the same price as in store.
6 people found this helpful
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Reviewed in the United States on February 8, 2017
This formula is a life saver. I used to exclusively breast feed for about three months and just recently I started supplementing with formula upon my return to work. For the first two months of his life, my son did what every breast fed baby does, which is poo after every feed; no issue. But as he got a bit older and the poops became less frequent, I started noticing that they caused him some distress. He had a BM only once a day or even less frequently and if he skipped a day, he started to get very miserable and fussy. He would often scream closing his eyes and clenching fists, as if in pain. Gas drops didn't help much and I knew that it was caused by going too long without a BM. When he was about three months old, I received an email from Enfamil advertising the Reguline formula and I ordered one can to try it. After reading reviews; which suggested that it really works and might even cause messy poops at first, I started by giving my son only one bottle of this formula per day. For the rest of his meals, he still drinks my breast milk. The Reguline works like magic -- since that first bottle, he now has a BM twice a day, which I find to be just right. The crying outbursts are gone, he feeds much better, and even seems to be taking longer naps, which I attribute to the fact that his belly feels much more comfy. If you have a little one who is constipated or even somewhat out of line, definitely give this product a try.
7 people found this helpful
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